The most important element of quality-control is to start with a clean lab and keep it clean. Lab personnel should adhere to all clean-room protocol.

Cleaning Procedures

Procedures to be completed when cleaning a Class 10,000 cleanroom:

A detailed cleaning schedule should be prepared for every cleanroom. Housekeeping maintenance of the cleanroom and restricted areas is essential to ensure quality. Cleaning of a cleanroom should be performed on a daily basis. Improper cleaning of the cleanroom can lead to contamination and a loss in end-user product quality.

Materials and Equipment

The following items should be purchased for and used only in the cleanroom:

• Mop bucket and wringer
• Mops
• Vacuum cleaner
• Wipes
• Cleaning and disinfecting solutions (such as Isopropyl Alcohol and Acetone)

Tasks

Frequency will vary depending upon local requirements.

• Change all Hepa pre-filters.
• Vacuum (if allowed) the floors and work surfaces.
• Empty appropriate trash and waste.
• Clean the equipment, doors, door frames and lockers in the pre-staging areas using the approved cleaning solution.
• Mop cleanroom floors.
• Clean all work surfaces in the controlled environment.